Конечно, вот несколько вариантов сделать данные предложения негативными и вопросительными:
1. Отрицательные предложения: - He doesn't read books in his free time. - He never reads books in his free time.
- He doesn't live in Moscow. - He no longer lives in Moscow.
2. Вопросительные предложения: - Does he not read books in his free time? - Doesn't he read books in his free time? - Is he not living in Moscow? - Isn't he living in Moscow? - Does he live in Moscow?